How Fasting & Caloric Restriction Impact Health | Dr. Satchin Panda & Dr. Andrew Huberman

So you're saying they either did caloric restriction portion control within a 10 hour window or another group within the study , eight sub maintenance calories . So , caloric restriction cr as we're calling it the acronym cr but restricted that to an eight hour feeding window and they didn't see any difference in terms of weight loss . But , but it's not all that surprising , right ?

How Fasting & Caloric Restriction Impact Health | Dr. Satchin Panda & Dr. Andrew Huberman

So there is a famous experiment that was published last year by J Takahi Islam and it came out in science and that relates to caloric restriction . And we kind of started with this idea .

How Fasting & Caloric Restriction Impact Health | Dr. Satchin Panda & Dr. Andrew Huberman

So they're eating in a 10 to 12 hour feeding window anyway . So you're saying they either did caloric restriction portion control within a 10 hour window or another group within the study , eight sub maintenance calories . So , caloric restriction cr as we're calling it the acronym cr but restricted that to an eight hour feeding window and they didn't see any difference in terms of weight loss .

How Fasting & Caloric Restriction Impact Health | Dr. Satchin Panda & Dr. Andrew Huberman

And we kind of started with this idea . Um We started discussing that the rat experiments were done with caloric restriction and researchers gave reduced calorie consumption by 20% or 30% and get that food , the rats and then subsequently mice and they all lived longer . What is interesting is um in all those experiments , um the researchers came and gave this bolus of food at one time , whereas they are lit on fed mice or rats , they had access to food all the time .

How Fasting & Caloric Restriction Impact Health | Dr. Satchin Panda & Dr. Andrew Huberman

So they are already eating for 10 hours and fasting for uh 14 hours . All participants had to reduce their calorie intake and they reduced by almost 25% . The cr group continued with 10 hours eating window and the cr plus time restricted group had to eat the same number of calories within eight hours .